In Vitro Anthelmintic Activity of Swietenia Mahagoni Seed Extracts against Pheritima Posthuma

Swietenia mahagoni belongs to Meliaceae family, native to West Indies. The plant is commonly known as “mahogani.’’ This timber tree is mainly cultivated in tropical zones such as India, Malaysia and Southern China. In the present study, Crude aqueous, chloroform and acetone extracts of Swietenia mahagoni seeds were evaluated for in-vitro anthelmintic activity on the Indian adult earthworms Pheritima posthuma. Among all the solvent extracts, aqueous extract showed potent activity (paralysis and death time was 07.74±0.26 and 23.47±0.19 min) as compared to chloroform and acetone extract at the concentration of 80mg/ml, while Piperazine citrate is used as standard drug (paralysis and death time was 8.03±0.32 and 15.39±0.28 min) at the concentration of 20mg/ml. Phytochemical analysis showed the presence of alkaloids, tannins and phenolic compounds may the active compounds.